Amplified Ingredients – supplier for metabolic and gut health

Pomegranate extract with molecular structure analysis for health ingredient formulation

From stability to bioavailability, every ingredient is chosen to perform

Amplified Ingredients is a health ingredients supplier and ingredient distributor serving formulators, manufacturers, and product developers around the world. We provide ingredient distribution with one clear focus: delivering ingredients that survive real-world conditions and provide measurable health benefits.

Where many wholesale ingredients distributors in the USA compete on catalog size, we take the opposite approach. Our portfolio is intentionally narrow — concentrating on metabolic health ingredients, probiotics, and nutrient-dense compounds chosen for their bioavailability, stability, and performance.

We work strictly with innovative brands and manufacturers, supporting teams who need more than commodity inputs. Whether the challenge is gut microbiome resilience, mitochondrial support, protection against toxins like glyphosate, or something else entirely, we partner with formulators to supply ingredients that transform both the finished product and the end user’s health.

Functional metabolic health ingredients & probiotic support

The real formulator’s dilemma is the constant tradeoff between what science says is possible and what the industry can actually deliver. Too often, formulators are forced to choose between stability and efficacy, label claims and real health outcomes, innovation and scalability. Those disparities kill promising ideas before they ever reach the shelf.

Amplified Ingredients was founded to close those gaps. We supply functional metabolic health ingredients and resilient probiotics designed from the ground up for performance under real world conditions — stable under heat, consistent in storage, bioavailable for the body, and proven in application. Instead of compromise, we give formulators the tools to turn strong science into products that truly transform health.

Ingredients that transform

At Amplified Ingredients, we don’t just supply — we develop. Our team helped pioneer two ingredients that are now redefining what’s possible for formulators.

Naturalin®

A highly soluble form of ellagic acid, once limited by poor absorption, now dissolving, dispersing, and delivering in real products.

Health Benefits

Early preclinical findings suggest it may support measurable improvements in blood sugar control and fat metabolism, pointing to a meaningful impact on metabolic health beyond formulation performance.

Bacillus subtilis AB22™

A heat-stable probiotic, proven to survive gummies, RTDs, and even the coffee-brewing process while maintaining its impact on gut and immune health.

Applications

For formulators, that means a probiotic that keeps its strength through processes that normally kill off live cultures — even high-heat brewing — and still delivers measurable gut and immune benefits.

KSM-66® Ashwagandha preferred US distributor

Amplified Ingredients is a preferred distributor of KSM-66®, the world’s most clinically studied ashwagandha extract. Backed by over two dozen gold-standard trials, it delivers proven benefits for stress, cognition, recovery, and resilience.

We support formulators and supply chain teams with domestic access to KSM-66®, along with formulation insight and technical guidance to help integrate this flagship adaptogen into new products with confidence.

Why we’re different from other ingredient suppliers

Why should you work with us instead of one of the hundreds of other health ingredient suppliers out there? Because our approach changes what you get out of the relationship. We’re not here to drop samples and move boxes—we’re here to ensure your formulations succeed. That’s why we focus on fewer ingredients, work closely with fewer partners, and measure success by scaled products, not catalogs or call volume.

What that means for you:

Focus over volume

A small portfolio centered on ingredients that change what’s possible in formulation — not a rolling list of me-too inputs.

Hands-on expertise

With deep roots in ingredient development and formulation, we work closely with partners to anticipate challenges and provide practical solutions from early concept through commercialization.

Performance in the real world

We prioritize stability, bioavailability, and survivability across formats, so results hold from pilot to production.

Outcomes that matter

Work aimed at crucial areas like metabolic health, mitochondrial support, gut microbiome resilience, and protection against environmental stressors such as glyphosate.

If you’re building a few products that need ingredients that actually perform — and you want a partner to help you scale them — let’s talk.

Frequently Asked Questions

Find quick answers to the most common questions about our ingredients and services.

Metabolic health refers to how well the body processes and uses energy. It represents an optimal, integrated state of systemic energy homeostasis, characterized by tightly regulated glucose and lipid flux, coupled with high insulin sensitivity across peripheral tissues—specifically adipose, skeletal muscle, and the liver.

Metabolic health is measured by the absence of dyslipidemia, maintenance of normoglycemia, and blood pressure within optimal reference ranges. Fundamentally, it reflects the efficiency of the organism’s capacity to dynamically adapt to energetic shifts (e.g., fasting/fed states) through coordinated neuro-endocrine signaling, thus sustaining cellular energy viability and limiting inflammatory stress.

Strong metabolic health supports energy, weight management, and long-term wellness.

Metabolic health ingredients are functional compounds, extracts, and nutrients specifically chosen to support the body’s metabolic processes. These ingredients encompass a refined class of bioactive compounds—such as specific complex dietary fibers, specialized peptides, and polyphenolic compounds (e.g., stilbenes and flavonoids)—that function primarily as cell signaling modulators.

The action of metabolic health ingredients often involves the allosteric activation or upregulation of key energy-sensing pathways, most notably the AMP-activated protein kinase (AMPK) and various Sirtuin families (SIRT1-7). By promoting GLUT4 translocation and optimizing the rate of hepatic gluconeogenesis, they enhance glucose disposal, ameliorate hepatic steatosis, and collectively support superior metabolic flexibility.

By supporting the body’s core energy-producing pathways, metabolic health ingredients help formulators create products that measurably support the health of consumers.

Mitochondrial health refers to how well the body’s mitochondria produce energy and regulate key cellular functions. It is the aggregate function of the organelle’s intrinsic quality control mechanisms, encompassing the dynamic balance of fission/fusion cycles, the efficiency of oxidative phosphorylation via the electron transport chain (ETC), and the rigor of the mitophagic process (selective autophagic degradation of dysfunctional mitochondria).

Optimal health ensures a robust mitochondrial membrane potential and minimal leakage of Reactive Oxygen Species, thereby maximizing the cellular ATP-to-ADP ratio.

Mitochondrial health ingredients are nutrients, antioxidants, and bioactive compounds that support the performance of mitochondria to produce energy and regulate metabolic processes. These are critical cofactors and nutrient precursors that directly support mitochondrial respiration and cellular defense.

Examples include highly soluble ellagic acid (e.g., NaturalinTM), which serves as a precursor for microbial metabolites known as urolithins, and NAD+ precursors (e.g., nicotinamide riboside or mononucleotide). Urolithins, specifically, are recognized for their role in stimulating the mitophagic process.

These Mitochondrial health ingredients are essential for protecting the integrity of the inner mitochondrial membrane, ensuring the necessary substrate flow for the ETC, and enhancing the overall rate of oxidative phosphorylation without escalating localized oxidative stress.

For formulators, these ingredients are critical tools for developing products that target factors like cardiovascular health, athletic performance, and healthy aging by directly supporting cellular energy pathways.

Nutrient density is precisely defined as the ratio of essential micronutrient mass (vitamins, trace minerals, and phylogenetically significant phytochemicals) relative to the constituent energy (calorie) content of a food item.

A superior measure of density is predicated on the essential principle of Organic Food Bound: nutrients that are naturally integrated or chelated within the food’s complex biochemical matrix. This intrinsic integration, rather than the use of isolated synthetic forms, enhances nutrient stability and provides the synergistic co-factors necessary for optimal metabolic processing and absorption.

For formulators, prioritizing nutrient density is crucial for creating products that deliver maximum nutritional and metabolic impact per serving.

Nutrient dense ingredients are specific compounds and extracts selected for their high concentration of bioavailable vitamins, minerals, and phytonutrients in relation to their caloric load. Unlike whole foods, these are often highly-purified or specialized materials designed to deliver targeted health benefits in a concentrated form that can survive a formulation and production process. These ingredients are characterized by an exceptional concentration of essential micronutrients embedded within a natural, complex food matrix.

Prime examples of nutrient dense ingredients include specialized plant botanicals, select microalgae, and certain animal-derived tissues (e.g., organ meats rich in highly bioavailable, pre-formed vitamins and heme iron). Their inherent density is derived from the synergistic blend of co-factors and transport molecules that naturally accompany the core nutrient payload, maximizing absorption and supporting cellular utilization via the Organic Food Bound matrix.

Bioavailability is the measure of how much of a nutrient, botanical, or bioactive compound is absorbed by the body and made available for use at its target site. Specifically, bioavailability is the quantitative fraction of an ingested nutrient that survives transit through the gastrointestinal tract and avoids first-pass hepatic metabolism to ultimately reach systemic circulation, making it available for biological activity at target tissues.

The process is governed by factors including the nutrient’s physiochemical properties, the efficiency of specific transmembrane transporters, the influence of the gut microbiota on xenobiotic metabolism, and, critically, the Organic Food Bound matrix of the source material which dictates release kinetics.

For formulators, higher bioavailability is critical to ensure that an ingredient consistently and efficiently delivers on its promised health benefits.

Ready to transform your products?

Connect with our ingredient experts to discover how our science-backed solutions can elevate your formulations and drive measurable results.